SciFinder (CAS)

The chemist’s index — substances, reactions, and literature.

At a Glance

PublisherCAS (a division of the American Chemical Society); the platform is SciFinder-n
Coveragethe CAS databases — 200M+ substances in the CAS Registry, reactions, and the chemistry literature (CAplus)
Accessinstitutional subscription
Free alternativePubChem (substances), Reaxys is the paid rival
Regionalglobal.

Our Take

SciFinder is the authoritative discovery tool in chemistry, uniquely combining the literature with the CAS Registry of substances and a vast reaction database — so you can search by structure, substructure, or reaction, not just keywords, which no general index supports. For chemists it’s close to indispensable. It’s a premium product, and its structure-search power assumes chemistry-specific skills. Use it for substance, structure, and reaction searching in chemistry; PubChem covers the free-substance layer and Reaxys is the main paid alternative.

Power Tips

  • Search by structure and reaction, not just text — SciFinder’s substance and reaction databases answer questions no keyword index can
  • use it to establish substance identity and synthesis routes, then trace the literature via CAplus.

Alternatives & Complements

Reaxys · PubChem · Web of Science · Scopus.